JapanStake
Pharmaceutical · Fiscal year end 12月末日

Carna Biosciences, Inc.

4572

カルナバイオサイエンス株式会社

FIGI BBG000P46D804572.T4572 JPCorp. no. 8140001022724

Latest half-year results

First half · fiscal year to 2026-12 · filed 2026-08-07

For the first half of the fiscal year to 2026-12: Revenue ¥0.4 billion (+59.8% YoY), Ordinary income ¥-1 billion, Net income ¥-1 billion.

This periodYear on year
Revenue¥401m+59.8%
Ordinary profit−¥1.0bn—
Net profit to owners−¥1.0bn—

From the securities report on EDINET, which states no forecast. History via /v1/companies/4572/earnings-releases.

Financials

Japan GAAP · consolidated · fiscal year to 2025-12-31
Revenue
¥579m
Net income
−¥2.2bn
ROE
—
Equity ratio
25.1%
Dividend / share
—
Employees
61
Revenue · ¥bn
FY2021: ¥2.0bn 2.02 FY2021FY2022: ¥1.4bn 1.39 FY2022FY2023: ¥1.6bn 1.63 FY2023FY2024: ¥0.6bn 0.64 FY2024FY2025: ¥0.6bn 0.58 FY2025
Net income · ¥bn
FY2021: −¥0.5bn -0.53 FY2021FY2022: −¥1.3bn -1.35 FY2022FY2023: −¥1.2bn -1.15 FY2023FY2024: −¥2.2bn -2.18 FY2024FY2025: −¥2.2bn -2.17 FY2025
Fiscal yearRevenueNet incomeTotal assetsNet assetsROEEPSOperating CF
2025-12-31¥579m−¥2,171m¥1,230m¥309m—¥-113.62−¥2,159m
2024-12-31¥636m−¥2,179m¥2,772m¥2,475m—¥-121.64−¥1,375m
2023-12-31¥1,626m−¥1,153m¥4,350m¥3,878m—¥-68.62−¥1,677m
2022-12-31¥1,387m−¥1,350m¥4,266m¥3,642m—¥-99.1−¥708m
2021-12-31¥2,018m−¥534m¥5,433m¥4,316m—¥-42.1−¥1,537m

Indicators

Computed by us from filings · fiscal year to 2025-12-31
MetricValuePercentile among listed companies
ROE, %——
Ordinary margin-3.70410.6
Equity ratio, %25.110.2
Revenue growth-0.08997.3
Net income growth0.003335.9
Operating cash flow / assets-1.75610.1
Policy-uncertainty measure0.00 Share of the report's text discussing policy-related uncertainty, by policy area. Proprietary text method.
Ownership activity 0 filer(s) stated they may make proposals in 365 days; 0 new 5% holder(s) in 180 days; net stake change +4.77pt in 90 days; 0.0% held by other listed companies.

Results wording balance: +0.09. Proprietary text method; it describes the wording only and does not interpret context.

Interest example: if all ¥690m of reported debt repriced by 50 basis points, a year's interest would rise by ¥3m. Our arithmetic only, not a forecast: fixed-rate debt and hedges are ignored.

Via /v1/companies/4572/indicators. Descriptive figures, not a rating and not investment advice.

From other filings

As the company states them
Internal control, 2026-03-26: see filing 上記の評価の結果、当社代表取締役社長[氏名省略]、2025年12月31日現在における当社グループの財務報告に係る内部統制は有効であると判断しました。 Filing

Segments, votes and tender offers

Stated in EDINET filings
Segments: Drug Discovery Business, Drug Discovery Support Business. /v1/companies/4572/segments
Latest voting result: 2026-03-25 · 定款一部変更の件 · passed. /v1/companies/4572/voting

Ownership changes

All companies →
  • 2026-11-06
    Decrease−1.08pt

    individual filer reduced holdings in Carna Biosciences, Inc. (4572) to 24.57% from 25.65%.

    01020304050
  • 2026-10-20
    Increase+7.02pt

    individual filer raised holdings in Carna Biosciences, Inc. (4572) to 13.68% from 6.66%.

    01020304050
  • 2026-10-20
    Threshold

    Holdings of individual filer in Carna Biosciences, Inc. (4572) moved above 10% (6.66% -> 13.68%).

    01020304050
  • 2026-10-19
    Decrease−1.59pt

    individual filer reduced holdings in Carna Biosciences, Inc. (4572) to 25.65% from 27.24%.

    01020304050
  • 2026-10-14
    Increase+1.52pt

    individual filer raised holdings in Carna Biosciences, Inc. (4572) to 6.66% from 5.14%.

    01020304050
  • 2026-10-09
    Decrease−1.10pt

    individual filer reduced holdings in Carna Biosciences, Inc. (4572) to 27.24% from 28.34%.

    01020304050
  • 2026-07-29
    Decrease−1.87pt

    individual filer reduced holdings in Carna Biosciences, Inc. (4572) to 28.34% from 30.21%.

    01020304050
  • 2026-06-02
    Decrease−1.29pt

    individual filer reduced holdings in Carna Biosciences, Inc. (4572) to 30.21% from 31.50%.

    01020304050
  • 2026-05-20
    Decrease−1.70pt

    individual filer reduced holdings in Carna Biosciences, Inc. (4572) to 31.50% from 33.20%.

    01020304050
  • 2026-05-20
    Amendment−1.70pt

    individual filer filed a correction to a 5% report on Carna Biosciences, Inc. (4572).

Trades by 5% holders

From the 60-day trade tables in 5% reports
¥239¥609¥979 2021-11-192026-10-30 2026-10-30 · sold 64,900 @ ¥342 · individual filer2026-10-28 · sold 20,000 @ ¥332 · individual filer2026-10-27 · sold 10,000 @ ¥331.5 · individual filer2026-10-26 · sold 12,000 @ ¥332.5 · individual filer2026-10-23 · sold 35,000 @ ¥328.7 · individual filer2026-10-22 · sold 50,000 @ ¥334.7 · individual filer2026-10-21 · sold 157,114 @ ¥245.73 · individual filer2026-10-14 · bought 1,709,500 @ ¥409.5 · individual filer2026-10-14 · sold 157,114 @ ¥247.53 · individual filer2026-10-08 · sold 157,114 @ ¥247.23 · individual filer2026-10-06 · bought 30,000 @ ¥361 · individual filer2026-10-06 · sold 157,114 @ ¥263.43 · individual filer2026-10-05 · sold 5,000 @ ¥450 · individual filer2026-08-17 · sold 157,114 @ ¥238.53 · individual filer2026-07-22 · sold 471,342 @ ¥239.73 · individual filer2026-07-21 · sold 20,000 @ ¥296.4 · individual filer2026-07-10 · sold 20,000 @ ¥325.65 · individual filer2026-06-26 · sold 20,000 @ ¥311.05 · individual filer2026-06-15 · sold 20,000 @ ¥349.6 · individual filer2026-05-27 · sold 333,867 @ ¥256.74 · individual filer2026-05-25 · sold 48,000 @ ¥430.35 · individual filer2026-05-13 · sold 500,801 @ ¥257.04 · individual filer2026-04-28 · sold 500,801 @ ¥246.24 · individual filer2024-10-11 · bought 1,050,600 @ ¥360 · Athos Capital Limited2024-10-10 · sold 489,600 @ ¥360 · Athos Capital Limited2023-03-07 · sold 75,000 @ ¥460.31 · individual filer2023-02-27 · sold 175,000 @ ¥460.31 · individual filer2023-02-20 · sold 200,000 @ ¥460.31 · individual filer2023-02-15 · sold 350,000 @ ¥460.31 · individual filer2023-02-06 · sold 100,000 @ ¥460.31 · individual filer2023-01-30 · sold 200,000 @ ¥460.31 · individual filer2023-01-27 · sold 150,000 @ ¥460.31 · individual filer2023-01-19 · sold 50,000 @ ¥460.31 · individual filer2023-01-17 · sold 100,000 @ ¥460.31 · individual filer2023-01-16 · sold 100,000 @ ¥462.31 · individual filer2023-01-11 · sold 200,000 @ ¥462.31 · individual filer2023-01-05 · sold 500,000 @ ¥471.31 · individual filer2022-12-26 · sold 300,000 @ ¥522.31 · individual filer2022-12-14 · sold 250,000 @ ¥582.31 · individual filer2022-04-20 · sold 50,000 @ ¥971.9 · individual filer2022-04-04 · sold 27,000 @ ¥971.9 · individual filer2022-03-25 · sold 30,000 @ ¥971.9 · individual filer2022-01-13 · sold 85,000 @ ¥978.9 · individual filer2021-11-19 · sold 40,000 @ ¥971.9 · individual filer
Bought SoldHover a dot for the trade
HolderPeriodNet sharesNet % of sharesAvg. filed priceRange
individual filer2025-09-29 – 2026-10-30+7,094,949+27.18pt¥259.81¥239–430
individual filer2025-11-27 – 2026-10-14+2,219,500+10.10pt¥408.78¥361–450
Athos Capital Limited2024-10-10 – 2026-04-13+96,000+0.52pt¥360¥360–360
individual filer2021-11-19 – 2023-08-01-1,426,300−8.58pt¥518.82¥460–979

Net shares and the average are our calculations. Prices are filed prices as stated by the filer, mostly for off-market trades; they are not market prices. Stock lending, custody transfers and option exercises are excluded from net shares. Every row via /v1/companies/4572/trades.

5% filings

Large shareholding reports on 4572
FiledFilerStakeChangeStated purpose
2026-11-06individual filer24.57%−1.08ptpure investment
2026-10-20individual filer13.68%+7.02ptpure investment
2026-10-19individual filer25.65%−1.59ptpure investment
2026-10-14individual filer6.66%+1.52ptpure investment
2026-10-09individual filer27.24%−1.10ptpure investment
2026-07-29individual filer28.34%−1.87ptpure investment
2026-06-02individual filer30.21%−1.29ptpure investment
2026-05-20individual filer31.50%−1.70ptpure investment
2026-05-20individual filer33.20%−1.70ptpure investment
2026-05-20individual filer34.90%+19.88ptpure investment

Cross-shareholdings

From the annual report's status of shareholdings
Listed strategic holdings
1 issues
Book value
¥17m
Sold in the year
— — issues
Bought in the year
¥17m 1 issues
Mutual, both reports
0
Held by listed cos.
0
HoldsBook valueShares vs. prior yearMutual
TOYO SECURITIES CO., LTD. 8614¥17m—no

Purposes, all holdings and mutual flags via /v1/companies/4572/cross-holdings. Share changes include stock splits.

Major shareholders

As of fiscal year end 2025-12-31
ShareholderSharesRatio
MSIP CLIENT SECURITIES955,6124.99%
individual holder555,5002.90%
小野薬品工業株式会社504,5002.63%
individual holder500,0002.61%
individual holder468,8002.44%
individual holder333,9001.74%
individual holder255,0001.33%
BNY GCM CLIENT ACCOUNT JPRD AC ISG (FE-AC)195,2411.02%
BNYM SA/NV FOR BNYM FOR BNYM GCM CLIENT ACCTS M ILM FE180,3040.94%
individual holder149,0000.77%

Get this as JSON

GET /v1/companies/4572
GET /v1/companies/4572/financials
GET /v1/companies/4572/details
GET /v1/companies/4572/segments
GET /v1/companies/4572/voting
GET /v1/companies/4572/tender-offers
GET /v1/companies/4572/indicators
GET /v1/companies/4572/earnings-releases
GET /v1/events?ticker=4572
GET /v1/companies/4572/trades         
GET /v1/companies/4572/cross-holdings 
GET /v1/companies/4572/brief          

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