JapanStake
Pharmaceutical · Fiscal year end Dec 31

Oncolys BioPharma Inc.

4588

オンコリスバイオファーマ株式会社

FIGI BBG00224MSK64588.T4588 JPCorp. no. 4010401053237

Latest half-year results

First half · fiscal year to 2026-12 · filed 2026-08-07

For the first half of the fiscal year to 2026-12: Revenue ¥0.5 billion (+1662.4% YoY), Ordinary income ¥-0.8 billion, Net income ¥-0.8 billion.

This periodYear on year
Revenue¥503m+1662.4%
Ordinary profit−¥761m—
Net profit to owners−¥762m—

From the securities report on EDINET, which states no forecast. History via /v1/companies/4588/earnings-releases.

Financials

Japan GAAP · non-consolidated · fiscal year to 2025-12-31
Revenue
¥29m
Net income
−¥2.1bn
ROE
—
Equity ratio
87.6%
Dividend / share
—
Employees
38
Revenue · ¥m
FY2021: ¥642m 642 FY2021FY2022: ¥976m 976 FY2022FY2023: ¥63m 63 FY2023FY2024: ¥31m 31.4 FY2024FY2025: ¥29m 28.5 FY2025
Net income · ¥bn
FY2021: −¥1.6bn -1.62 FY2021FY2022: −¥1.1bn -1.15 FY2022FY2023: −¥1.9bn -1.94 FY2023FY2024: −¥1.7bn -1.68 FY2024FY2025: −¥2.1bn -2.06 FY2025
Fiscal yearRevenueNet incomeTotal assetsNet assetsROEEPSOperating CF
2025-12-31¥29m−¥2,058m¥4,556m¥4,000m—¥-80−¥1,941m
2024-12-31¥31m−¥1,685m¥3,199m¥2,752m—¥-77.17−¥2,020m
2023-12-31¥63m−¥1,939m¥2,041m¥1,474m—¥-108.92−¥1,337m
2022-12-31¥976m−¥1,149m¥2,651m¥2,159m—¥-66.31−¥1,717m
2021-12-31¥642m−¥1,615m¥4,292m¥3,594m—¥-95.5−¥1,742m

Indicators

Computed by us from filings · fiscal year to 2025-12-31
MetricValuePercentile among listed companies
ROE, %——
Ordinary margin-71.85750.1
Equity ratio, %87.697
Revenue growth-0.09047.3
Net income growth-0.221621.8
Operating cash flow / assets-0.4260.9
Policy-uncertainty measure0.46 Share of the report's text discussing policy-related uncertainty, by policy area. Proprietary text method.
Trade & tariffs 1 Politics & geopolitics 1
Ownership activity 0 filer(s) stated they may make proposals in 365 days; 0 new 5% holder(s) in 180 days; net stake change 0.00pt in 90 days; 2.5% held by other listed companies.

Results wording balance: -1.00. Proprietary text method; it describes the wording only and does not interpret context.

Interest example: if all ¥300m of reported debt repriced by 50 basis points, a year's interest would rise by ¥1m. Our arithmetic only, not a forecast: fixed-rate debt and hedges are ignored.

Via /v1/companies/4588/indicators. Descriptive figures, not a rating and not investment advice.

From other filings

As the company states them
Internal control, 2026-03-25: see filing 上記の評価の結果、当事業年度末日時点において、当社の財務報告に係る内部統制は有効であると判断いたしました。 Filing

Segments, votes and tender offers

Stated in EDINET filings
Latest voting result: 2026-03-24 · 取締役5名選任の件 · passed. /v1/companies/4588/voting

Ownership changes

All companies →

Trades by 5% holders

From the 60-day trade tables in 5% reports
¥540¥569¥597 2024-08-132024-10-16 2024-10-16 · sold 1,600 @ ¥597.43 · Evo Fund2024-10-16 · sold 1,600 @ ¥597.43 · Evolution Capital Management LLC2024-10-15 · sold 6,800 @ ¥578.42 · Evo Fund2024-10-15 · sold 6,800 @ ¥578.42 · Evolution Capital Management LLC2024-10-11 · sold 4,300 @ ¥565.99 · Evo Fund2024-10-11 · sold 4,300 @ ¥565.99 · Evolution Capital Management LLC2024-10-10 · sold 9,200 @ ¥556.95 · Evo Fund2024-10-10 · sold 9,200 @ ¥556.95 · Evolution Capital Management LLC2024-10-09 · sold 600 @ ¥540.43 · Evo Fund2024-10-09 · sold 600 @ ¥540.43 · Evolution Capital Management LLC2024-10-03 · sold 100 @ ¥562.1 · Evo Fund2024-10-03 · sold 100 @ ¥562.1 · Evolution Capital Management LLC2024-10-01 · sold 200 @ ¥570.1 · Evo Fund2024-10-01 · sold 200 @ ¥570.1 · Evolution Capital Management LLC2024-09-27 · sold 100 @ ¥572.1 · Evo Fund2024-09-27 · sold 100 @ ¥572.1 · Evolution Capital Management LLC2024-09-24 · sold 100 @ ¥581.1 · Evo Fund2024-09-24 · sold 100 @ ¥581.1 · Evolution Capital Management LLC2024-09-20 · sold 900 @ ¥586.18 · Evo Fund2024-09-20 · sold 900 @ ¥586.18 · Evolution Capital Management LLC2024-09-19 · sold 300 @ ¥571.1 · Evo Fund2024-09-19 · sold 300 @ ¥571.1 · Evolution Capital Management LLC2024-09-18 · sold 400 @ ¥558.13 · Evo Fund2024-09-18 · sold 400 @ ¥558.13 · Evolution Capital Management LLC2024-08-13 · sold 1,200 @ ¥574.15 · Evo Fund2024-08-13 · sold 1,200 @ ¥574.15 · Evolution Capital Management LLC
Bought SoldHover a dot for the trade
HolderPeriodNet sharesNet % of sharesAvg. filed priceRange
individual filer2025-11-10 – 2026-05-14+165,000+0.55pt——
SMBC日興証券株式会社2023-05-26 – 2025-10-20+4,430,200+17.49pt——
株式会社 三井住友銀行2023-06-28 – 2025-10-2000.00pt——
Evo Fund2024-06-14 – 2024-10-16+706,000+2.83pt¥567.75¥540–610
Evolution Capital Management LLC2024-06-14 – 2024-10-16+706,000+2.83pt¥567.75¥540–610

Net shares and the average are our calculations. Prices are filed prices as stated by the filer, mostly for off-market trades; they are not market prices. Stock lending, custody transfers and option exercises are excluded from net shares. Every row via /v1/companies/4588/trades.

5% filings

Large shareholding reports on 4588
FiledFilerStakeChangeStated purpose
2026-05-20individual filer3.91%−1.13ptpure investment
2026-02-05Morgan Stanley MUFG Securities Co., Ltd.2.77%−2.79pt—
2026-01-21Morgan Stanley MUFG Securities Co., Ltd.5.56%−0.23pt—
2026-01-16individual filer5.04%—pure investment
2026-01-08Morgan Stanley MUFG Securities Co., Ltd.5.79%——
2025-11-21SMBC Nikko Securities Inc.4.58%−4.50pt—
2025-10-27SMBC Nikko Securities Inc.9.08%−1.09pt—
2025-10-17SMBC Nikko Securities Inc.10.17%−0.68pt—
2025-10-14SMBC Nikko Securities Inc.10.85%−1.09pt—
2025-10-06SMBC Nikko Securities Inc.11.94%−0.89pt—

Cross-shareholdings

From the annual report's status of shareholdings
Listed strategic holdings
— issues
Book value
—
Sold in the year
— — issues
Bought in the year
— — issues
Mutual, both reports
0
Held by listed cos.
1

Held by: Astellas Pharma Inc. 4503

Purposes, all holdings and mutual flags via /v1/companies/4588/cross-holdings. Share changes include stock splits.

Major shareholders

As of fiscal year end 2025-12-31
ShareholderSharesRatio
アステラス製薬株式会社727,2002.48%
モルガン・スタンレーMUFG証券株式会社653,7002.23%
individual holder520,7001.77%
YUANTA SECURITIES CO., LTD-RETAIL ACCOUNT388,4001.32%
individual holder300,0001.02%
株式会社SBI証券287,7140.98%
individual holder272,2000.92%
野村證券株式会社271,6700.92%
UBS証券株式会社267,4540.91%
individual holder255,1000.87%

U.S. funds holding 4588

SEC Form N-PORT, reports to 2026-07-31

1 U.S. funds held 1,600 shares worth $0.0m.

FundSharesValue% of fundAs of
iShares Neuroscience and Healthcare ETF
iShares Trust
1,600$0.0m0.480%2026-07-31

Up to 25 funds per stock via the API.

Get this as JSON

GET /v1/companies/4588
GET /v1/companies/4588/financials
GET /v1/companies/4588/details
GET /v1/companies/4588/segments
GET /v1/companies/4588/voting
GET /v1/companies/4588/tender-offers
GET /v1/companies/4588/indicators
GET /v1/companies/4588/earnings-releases
GET /v1/events?ticker=4588
GET /v1/companies/4588/trades         
GET /v1/companies/4588/cross-holdings 
GET /v1/companies/4588/brief          

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